Dr. Edward F. Group – Due to vitamin B-12’s association with energy metabolism, you might wonder what purpose it serves in your brain’s health and memory. There are a few complex roles that this B vitamin participates in — beyond releasing energy — that play a role in neurological function. This article will shed light on the primary reasons B-12 is indispensable to healthy brain aging.

Vitamin B-12 primarily functions as an enzyme cofactor. This role includes the production of red blood cells, the synthesis of myelin (a protein that coats nerves), genetic expression, amino acid balance, and the detoxification of hormones, neurotransmitters, and other chemicals. These activities are essential to maintaining brain function and preventing memory loss and cognitive decline.^{[1, 2]}

B-12 Deficiency and Cognitive Impairment

A number of brain diseases are associated with low B-12 status, particularly conditions characterized by cognitive difficulties like muddled thinking and forgetfulness. But the precise mechanism wasn’t identified until relatively recently. Researchers and doctors are beginning to see that cognitive issues associated with advanced age might be due, at least in part, to undiagnosed low B-12 status.^{[1, 3]} Continue reading →