Dr. Edward F. Group – If you have a leaky gut – also called increased intestinal permeability – substances that should stay in the gastrointestinal (GI) tract pass through spaces called tight junctions. In a healthy gut, tight junctions act like gatekeepers, keeping partially digested food and microbiota in and allowing nutrients out as needed. But if physical damage, chemical damage, pathogens, or illness injures the GI tract, the tight junctions loosen, leading to a leaky gut. A leaky gut is a risk factor for developing other conditions, including Crohn’s Disease, autoimmune and neurological disorders, and allergies.
What Exactly Is the Gut?
The gut, or gastrointestinal system, includes everything from the mouth to the anus – with the esophagus, stomach, small and large intestine (colon) in between. The small intestine and large intestine[1] contain roughly 2,700 square feet of surface area, which is about the size of a tennis court.[2] Finger-like projections called villi line the intestinal wall and help with nutrient absorption. Continue reading